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LAB-Bench CloningScenarios (SecureBio)

Science

SecureBio's own runs of LAB-Bench CloningScenarios without tool use. These are the same 33 public questions as lab-bench-cloningscenarios under a different protocol. Evaluated in Inspect with zero-shot prompting, usually over 10 runs. SecureBio doesn't state how refusals enter accuracy. Claude Opus 4.8 prints 95.9% with 46.7% refused, more than it could score if refusals counted as wrong, so accuracy appears to cover answered questions only and each model's denominator differs. These scores aren't comparable with other runs of the test, which is why this is a diagnostic.

Benchmark source: Securebio

Top models (higher is better)

ModelScoreSource
Claude Opus 5100.0SecureBio Biology Benchmark Dashboard · SecureBio
Gemini 3.8 Flash100.0SecureBio Biology Benchmark Dashboard · SecureBio
Gemini 4 Argon100.0SecureBio Biology Benchmark Dashboard · SecureBio
Gemini 3.7 Flash99.4SecureBio Biology Benchmark Dashboard · SecureBio
GPT-5.597.3SecureBio Biology Benchmark Dashboard · SecureBio
Gemini 3.6 Flash96.1SecureBio Biology Benchmark Dashboard · SecureBio
Opus 4.895.9SecureBio Biology Benchmark Dashboard · SecureBio
Grok 4.694.2SecureBio Biology Benchmark Dashboard · SecureBio
Gemini 3 Pro Preview94.1SecureBio Biology Benchmark Dashboard · SecureBio
Gemini 3.5 Flash93.9SecureBio Biology Benchmark Dashboard · SecureBio
Qwen3.8 2.4T A95B92.6SecureBio Biology Benchmark Dashboard · SecureBio
GPT-5.6 Terra92.5SecureBio Biology Benchmark Dashboard · SecureBio
Kimi K3.1 Pro91.5SecureBio Biology Benchmark Dashboard · SecureBio
Gemini 3 Flash Preview82.7SecureBio Biology Benchmark Dashboard · SecureBio
GPT-5.478.5SecureBio Biology Benchmark Dashboard · SecureBio
Opus 4.575.2SecureBio Biology Benchmark Dashboard · SecureBio
GPT-5 Pro73.3SecureBio Biology Benchmark Dashboard · SecureBio
GPT-565.3SecureBio Biology Benchmark Dashboard · SecureBio
Beam 1.0 501B A23B64.3SecureBio Biology Benchmark Dashboard · SecureBio
Gemini 2.5 Pro63.9SecureBio Biology Benchmark Dashboard · SecureBio
o363.3SecureBio Biology Benchmark Dashboard · SecureBio
Sonnet 4.561.8SecureBio Biology Benchmark Dashboard · SecureBio
Opus 4.160.5SecureBio Biology Benchmark Dashboard · SecureBio
Muse Glimmer 30B60.4SecureBio Biology Benchmark Dashboard · SecureBio
Gemini 2.5 Pro Preview 05-0660.2SecureBio Biology Benchmark Dashboard · SecureBio
Gemini 3.1 Pro Preview57.3SecureBio Biology Benchmark Dashboard · SecureBio
Grok 4 Fast55.6SecureBio Biology Benchmark Dashboard · SecureBio
Opus 453.6SecureBio Biology Benchmark Dashboard · SecureBio
GPT-5.153.3SecureBio Biology Benchmark Dashboard · SecureBio
o4-mini50.0SecureBio Biology Benchmark Dashboard · SecureBio
Claude 3.5 Sonnet (Oct 2024)49.4SecureBio Biology Benchmark Dashboard · SecureBio
Gemma 4 31B IT49.3SecureBio Biology Benchmark Dashboard · SecureBio
Inkling48.2SecureBio Biology Benchmark Dashboard · SecureBio
Sonnet 446.5SecureBio Biology Benchmark Dashboard · SecureBio
Grok 4.1 Fast46.0SecureBio Biology Benchmark Dashboard · SecureBio
Mistral Medium 3.543.5SecureBio Biology Benchmark Dashboard · SecureBio
Haiku 4.542.7SecureBio Biology Benchmark Dashboard · SecureBio
GPT-5 Mini42.7SecureBio Biology Benchmark Dashboard · SecureBio
o3-mini42.4SecureBio Biology Benchmark Dashboard · SecureBio
GPT-4.141.8SecureBio Biology Benchmark Dashboard · SecureBio
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